PROT-ON

Specify your run name*

Choose / Upload your protein complex*

Enter a PDB ID

Or upload a PDB file.

Which dimer chains should be analyzed?* Pick the monomer for mutational scanning*

(Per run, only one monomer can be analyzed)

Define interface selection cut-off

(Default 5Å)

Cut-off:

Identify the threshold to select the most enriching & depleting mutations

(Default 1.5)

IQR whisker threshold:

Evolutionary Filter (Optional)

Upload a PSSM (Position Specific Scoring Matrix) file to filter out the predictions according to the evolutionary information (example PSSM file)

E-mail (Optional)

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